What’s New To Stay Young?

Q: When senolytic drugs cause senescent cells to die, other (younger) cells need to divide and take the place of the dead cells. This cell division causes telomere shortening, thus possibly creating new senescent cells. How is it that the process of killing senescent cells is not self-defeating if new senescent cells are being created? There are a couple of ways to come at this question. The first is to just look at the astonishing beneficial effects of senolytic drugs or gene therapies in aging mice and mouse models of age-related disease.1,2 In these studies, senolytic drugs have restored exercise capacity1 and capacity...

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Alzheimer’s Prevention

Alzheimer’s Prevention

The month of June is draped in purple, dedicated to Alzheimer’s and Brain Awareness. At present, Alzheimer’s Disease (AD) is not a curable disease. The prevalence of AD in our aging population is frightening, affecting 10% of those over age 60, 20% of those over age 70, and 30% of those over age 80. There are roughly 5 to 6 million AD patients in the US and an equal number of people with mild cognitive impairment (MCI), memory loss, but not enough loss of function to be called AD. In general, MCI is a precursor to AD, with 80% eventually developing AD, at the...

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Food For Anti-aging

Food For Anti-aging

As we age and begin to feel our own mortality, many of us secretly fantasize about a “fountain of youth” that we can drink from, and which will turn back the clock on Father Time. But so far, no such fountain has been found, at least, not that anyone is talking about. So we do other things in an attempt to look and feel younger. We buy fancy skin creams, most of which are just garbage in a jar. We spend more time at the gym or following fitness regimens at home – and of course, there is nothing wrong...

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The World Congress of Anti Aging Medine April 2-6 Monaco

The World Congress of Anti Aging Medine April 2-6 Monaco

Hall Longevity Clinic Will Be Representing Miami in Monaco! Under the scientific supervision of the World Society of Interdisciplinary Anti-Aging Medicine (WOSIAM), the conference will feature a highly interactive, stimulating and multidisciplinary program and will provide the ideal forum to stimulate ideas, educate, share expertise, initiate intense discussions and extend networking opportunities. Many distinguished physicians, medical experts and scientists have joined the faculty and will take part in this congress. Every year, this highly awaited event attracts over 10 000 participants coming from more than 120 countries. Over 300 leading international companies, showcasing on the 5-floor exhibition area, will be there to let you discover their latest products,...

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CRISPR Gene Editing Makes Stem Cells ‘Invisible’ to Immune System

CRISPR Gene Editing Makes Stem Cells ‘Invisible’ to Immune System

UC San Francisco scientists have used the CRISPR-Cas9 gene-editing system to create the first pluripotent stem cells that are functionally “invisible” to the immune system, a feat of biological engineering that, in laboratory studies, prevented rejection of stem cell transplants. Because these “universal” stem cells can be manufactured more efficiently than stem cells tailor-made for each patient – the individualized approach that dominated earlier efforts – they bring the promise of regenerative medicine a step closer to reality.  “Scientists often tout the therapeutic potential of pluripotent stem cells, which can mature into any adult tissue, but the immune system has...

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AETHERN® The Formula

AETHERN® The Formula

Liquid “Shot” Formula AETHERN®’s proprietary formula is unique, indeed: it reinforces and enhances all the active ingredients, increasing the power of the nutritional action of the whole product. AETHERN® The Formula Formulated after extensive study, AETHERN®’s research team carefully chose the best and most active, top quality ingredients to improve skin condition on three fundamental levels: hydration, firmness and photo protection from too much sunlight. To ensure maximum bioavailability, AETHERN® formulators meticulously studied the synergy between each ingredient, to secure higher effectiveness and multiply the benefits of the final product. In fact, our balanced, Mediterranean polyphenol blend — a mixture of antioxidants and anti-inflammatory...

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Can you use facial rejuvenation safely?

Can you use facial rejuvenation safely?

As a doctor, I understand why men and women want to fight facial signs of aging: no one wants to wake up in the morning to a face that is wrinkled, with a double chin, and baggy eyes. The key to utilizing facial rejuvenation techniques is not to go overboard. Not too long ago MTV did a reality TV show entitled I Hate My Face. The show featured people who were addicted to cosmetic surgery and were only temporarily satisfied with its results. This temporary satisfaction gave them a high, one that did not last forever. After they came “down,”...

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What if the Placebo Effect Isn’t a Trick?

What if the Placebo Effect Isn’t a Trick?

The Chain of Office of the Dutch city of Leiden is a broad and colorful ceremonial necklace that, draped around the shoulders of Mayor Henri Lenferink, lends a magisterial air to official proceedings in this ancient university town. But whatever gravitas it provided Lenferink as he welcomed a group of researchers to his city, he was quick to undercut it. “I am just a humble historian,” he told the 300 members of the Society for Interdisciplinary Placebo Studies who had gathered in Leiden’s ornate municipal concert hall, “so I don’t know anything about your topic.” He was being a little...

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The Quest for Eternal Youth

The Quest for Eternal Youth

For centuries, writers, artists, and explorers have spoken about the myth surrounding an eternal, magical fountain that provides youthful restoration to anyone who bathes or drinks from it. In the late 1800’s, the prestigious Elms Hotel, located in what is now known as Excelsior Springs, Missouri, began sending out brochures describing something quite close to this fountain. The springs around the hotel produced healing mineral waters that helped to treat and cure some complex ailments like tuberculosis, syphilis and even severe wounds from battle. A paleontologist visiting the area claimed that “Nature itself set a plan for the town of...

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Rapamycin and TOR

Rapamycin and TOR

Of all the known chemical substances in the universe, a single drug has emerged as the most robust in extending lifespan. That drug has extended the lifespan of every living thing tested in the laboratory: yeast, worms, flies, and even middle-aged mice. That drug is Rapamycin. In a recent 2014 paper, it was reported rapamycin extended the median lifespan 23% in male mice and 26% in female mice. It has been known since the 1930s that caloric restriction extends lifespan and slows aging. Rapamycin could be characterized as caloric restriction in a pill. In a mouse study discussed in the “Cardiomyopathy” section, rapamycin had...

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