Is sex really so complicated?  Honestly, it’s very complicated and the common banter around the catch term “androgens”, such as testosterone, DHE-S, DHT, (particularly testosterone), have been shown to have both central and peripheral effects… that mean on therein and the penis itself…which can influence both libido and penile erection (Traish et al., 2007; Buvat et al., 2010). They are necessary (although not sufficient) for sexual desire in men, are essential in the maintenance of libido, and have an important role in regulating erectile capacity (Mills et al., 1996; Gray et al., 2005; Gooren and Saad, 2006; Traish et al., 2007; Buvat et al., 2010).

In men with normal gonadal function, however, there is no correlation between circulating testosterone levels and measures of sexual interest, activity, or erectile function (Krause and Müller, 2000). After castration in the male or other causes leading to a reduction in androgen levels, there is generally a decline in libido, and sometimes in erectile and ejaculatory functions.  Morning erections in men can be used as a barometer for sexual prowess and a “dip stick” of testosterone levels.

Bi-weekly testosterone administration of about 200mg of testosterone cypionate restores sexual interest and associated sexual activity in hypogonadal or castrated adult men (Skakkebaek et al., 1981; O’Carroll et al., 1985; Traish et al., 2007; Buvat et al., 2010). The testosterone dose-response relationships for sexual function and visuospatial cognition differ in older and young men; higher testosterone doses are needed in the elderly for normal sexual functioning (Gray et al., 2005).

Much more to follow!